Hot off the press! The Journal of Bone and Joint Surgery (JBJS) published results of the collaborative study between the Department of Human Physiology at University of Oregon and the Slocum Research and Education Foundation finding supplementation with essential amino acids reduces muscle loss following total knee arthroplasty. 

A double-blind, randomized, controlled study of 39 adults undergoing primary unilateral total knee arthroplasty (TKA) were measured and tested for muscle atrophy pre- and post-operative. During the study participants were given 20g twice daily of essential amino acid supplement between meals. MRI and functional testing were used to measure physical outcomes of surgery. Data on physical activity, diet and patient-reported outcomes (Veterans RAND 12-Item Health Survey and Knee Injury and Osteoarthritis Outcome Scores) were collected.  

Compared with baseline, the EAA group had significantly less decrease in mean quadriceps and hamstring muscle volume compared with the placebo group in the involved leg and the contralateral leg. The results of the study suggest that EAA supplementation is safe and reduces the loss of muscle volume in older adults recovering from TKA.

Article Citation & Link

Dreyer, Hans C.; Owen, Erin C.; Strycker, Lisa A.; Smolkowski, Keith; Muyskens, Jonathan B.; Kirkpatrick, Tessa K.; Christie, Anita D.; Kuehl, Kerry S.; Lantz, Brick A.; Shah, Steven N.; Mohler, Craig G.; Jewett, Brian A. Essential amino acid supplementation mitigates muscle atrophy after total knee arthroplasty: A randomized, double-blind, placeb-controlled trial. Journal of Bone & Joint Surg Open Access, 2018: e0006. Link to article. 

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